Table 9 Genes upregulated between 15- and 20-fold in peripheral blood mononuclear cells of patients with AECOPD compared to patients with stable COPD a
AE-1 vs stable | AE-3 vs stable | AE-10 vs stable | |||
|---|---|---|---|---|---|
Fold changes | Genes | Fold changes | Genes | Fold changes | Genes |
15.6 | ADM | 15.2 | LOC387763 | 15.0 | VSIG4 |
15.8 | DEFA4 | 15.2 | MMP25 | 15.6 | IL1RL1 |
16.2 | DEFA4 | 15.3 | USP15 | 15.8 | PZP |
16.2 | C1R | 15.5 | C1R | 16.0 | LDB2 |
16.9 | GPNMB | 15.8 | KCNJ15 | 16.2 | FLJ43663 |
17.2 | DCN | 15.9 | GADD45A | 16.5 | N/A |
17.3 | FAM46C | 15.9 | LRRC4 | 16.6 | CD55 |
17.6 | ALAS2 | 16.3 | GLT1D1 | 16.8 | CXCL2 |
17.6 | CALCA | 16.4 | CD55 | 16.9 | IL1RL1 |
17.9 | GPNMB | 16.5 | CEACAM6 | 17.0 | RHOB |
18.2 | DUSP1 | 16.6 | SPP1 | 17.1 | DLC1 |
18.2 | CEACAM6 | 16.7 | SLC25A37 | 17.2 | VIPR1 |
18.2 | SLC25A37 | 17.1 | ORM1 | 17.2 | CRYAB |
18.7 | FOS | 17.2 | CALCA | 17.8 | CNN3 |
18.9 | SLC25A37 | 17.3 | DUSP1 | 18.1 | DCN |
| Â | Â | 17.5 | CD177 | 18.1 | IFI27 |
| Â | Â | 17.6 | GPNMB | 18.2 | SLIT2 |
| Â | Â | 17.7 | MS4A3 | 18.3 | RASIP1 |
| Â | Â | 17.8 | DCN | 18.8 | MFAP4 |
| Â | Â | 17.8 | GPR109A | 19.0 | CAMK2N1 |
| Â | Â | 17.9 | BASP1 | 19.0 | CD55 |
| Â | Â | 17.9 | IL8RB | 19.5 | AGER |
| Â | Â | 18.4 | AQP9 | 19.9 | DKFZP686A01247 |
| Â | Â | 18.7 | DEFA4 | Â | Â |
| Â | Â | 18.8 | QPCT | Â | Â |
| Â | Â | 19.0 | PBEF1 | Â | Â |
| Â | Â | 19.0 | BASP1 | Â | Â |
| Â | Â | 19.0 | CEACAM6 | Â | Â |
| Â | Â | 19.2 | GNG10 | Â | Â |
| Â | Â | 19.7 | GPNMB | Â | Â |
| Â | Â | 19.7 | GCA | Â | Â |
| Â | Â | 20.0 | RNASE3 | Â | Â |