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Table 7 Genes upregulated >30-fold in peripheral blood mononuclear cells of patients with AECOPD compared to patients with stable COPD a

From: Dynamic gene expressions of peripheral blood mononuclear cells in patients with acute exacerbation of chronic obstructive pulmonary disease: a preliminary study

AE-1 vs stable

AE-3 vs stable

AE-10 vs stable

Fold changes

Genes

Fold changes

Genes

Fold changes

Genes

37.3

MMP8

33.2

LOC646309

30.0

CCDC48

37.6

CEACAM5

34.7

SERPINE1

31.9

LOC653509

38.6

PLUNC

34.9

FOS

32.0

EPAS1

39.4

BPIL1

37.6

CYR61

32.2

CDH5

40.3

CYR61

39.5

CEACAM5

34.4

CLDN5

45.4

CEACAM5

39.6

PLUNC

36.3

SEPP1

55.2

CALCA

40.1

ARG1

38.7

CAV1

56.0

VSIG4

43.5

BPIL1

39.2

CYR61

103.9

CA1

46.0

CEACAM5

42.1

ADH1B

  

85.9

CALCA

44.2

CTGF

    

44.9

CAV1

    

45.1

GPRC5A

    

49.8

SEPP1

    

81.4

GPX3

  1. aData are from patients with patients with acute exacerbation of chronic obstructive pulmonary disease on day 1 (AE-1), day 3 (AE-3) and day 10 (AE-10) of hospital admission, as compared to patients with stable chronic obstructive pulmonary disease (Stable).