Table 15 Genes downregulated more than fivefold in peripheral blood mononuclear cells of patients with AECOPD compared to patients with stable COPD ^a

5.0

PRODH

10.2

KSP37

10.1

LOC646781

5.1

MT1F

10.3

DUB3

10.1

LOC389634

5.1

OR2A7

10.6

DUB3

10.1

LOC441056

5.3

CD8B

10.8

TCF7

10.1

LOC340243

5.4

CGI-38

11.2

CX3CR1

10.2

C1QL2

5.4

DMBT1

17.6

MGC35295

10.2

LOC653541

5.4

N/A

19.9

STAC2

10.2

LOC158318

5.4

GNLY

25.0

AZGP1

10.3

N/A

5.5

LCK

10.4

LOC644373

5.5

DZIP1

10.6

SPDEF

5.6

TCF7

10.7

DUX1

5.6

MGC45438

10.9

LOC643001

5.6

UNQ470

11.1

LOC391767

5.8

MGLL

11.2

LOC645509

5.8

B4GALNT3

11.7

FLJ36131

5.9

CGI-38

11.8

LOC441323

5.9

CGI-38

11.9

LOC440015

6.1

LOC388886

11.9

LOC441812

6.1

GNLY

12.0

TCEB3C

6.2

N/A

12.1

SPDEF

6.4

CD8B

12.3

DUX4

6.4

AEBP2

12.5

LOC285697

6.4

EDG8

12.9

LOC646066

6.5

PRDM16

13.3

LOC441873

6.8

CX3CR1

13.6

LOC645402

7.0

MGC45438

13.7

LOC285563

7.3

MST1

13.9

LOC391763

7.4

LOC644088

14.4

DUB3

7.5

EDG8

14.7

LOC391766

10.1

MGC45438

15.0

LOC392197

12.6

MGC35295

15.0

REXO1L2P

15.5

STAC2

15.2

DUB3

19.1

AZGP1

15.2

LOC402199

15.7

LOC653442

15.8

LOC653455

16.0

LOC402207

16.5

LOC391745

16.7

LOC392188

18.1

REXO1L6P

19.1

LOC391764

19.4

DUB3

20.6

LOC645836

21.0

LOC391749

23.8

LOC402110

24.2

REXO1L7P

29.6

REXO1L1

30.0

STAC2

33.5

REXO1L3P

39.7

REXO1L5P