Table 14 Genes downregulated between six- and eightfold in peripheral blood mononuclear cells of patients with stable COPD or AECOPD compared to healthy control subjects ^a

6.0

NDUFV3

6.0

MAL

6.0

IL7R

6.0

HKDC1

6.0

C17orf45

6.0

ARHGAP12

6.0

CD28

6.1

TANC2

6.1

MAL

6.0

TRAPPC4

6.0

KIR2DS1

6.1

FAM5B

6.1

CXCR6

6.0

GNLY

6.0

FLJ20647

6.2

KIAA0748

6.1

SUCLA2

6.0

N/A

6.1

N/A

6.3

CD40LG

6.1

C21orf7

6.0

LOC642376

6.1

CLDN1

6.3

PCDH10

6.2

TNPO1

6.0

MYOZ3

6.1

TRBV5-4

6.3

LOC644273

6.2

LOC643514

6.1

FLJ20647

6.1

CARD11

6.3

CD96

6.2

ALS2CR13

6.1

CD96

6.1

LOC441320

6.3

TRA@

6.2

CREB1

6.2

MAL

6.1

ACADSB

6.3

TRBV3-1

6.2

C17orf45

6.2

GIMAP5

6.1

NXPH4

6.4

TRA@

6.3

NELL2

6.2

CLDN1

6.2

SCNN1D

6.4

LOC642483

6.3

C6orf32

6.2

CD3D

6.2

MTMR1

6.5

ANKDD1A

6.3

LOC642455

6.2

LY9

6.2

MAL

6.5

N/A

6.4

GMDS

6.3

LOC123876

6.2

ZAP70

6.5

N/A

6.4

ABHD6

6.3

TNFRSF25

6.3

MAL

6.5

LY9

6.4

DAPP1

6.3

C21orf7

6.3

IL2RB

6.6

CD8B

6.4

SH3BGRL

6.3

LOC645885

6.3

EDG8

6.6

MGC26597

6.5

IL7R

6.3

BLOC1S3

6.3

HKDC1

6.7

TRBV19

6.6

LOC441601

6.3

LOC644727

6.3

SCAP1

6.7

LOC145783

6.6

GPR18

6.4

CCDC45

6.3

LOC440455

6.8

CD8B

6.7

P2RX5

6.4

C21orf7

6.3

CD300E

6.9

C21orf7

6.7

LY9

6.5

CD28

6.4

LY9

6.9

UBASH3A

6.8

GGPS1

6.5

LOC440455

6.4

KIR2DS2

7.0

LOC400768

6.8

EIF3S6

6.5

IL24

6.4

SLAMF6

7.1

CD8B

6.8

ARHGAP15

6.5

GHRL

6.4

SAA3P

7.1

HAND1

6.8

SF3B1

6.5

FAM113B

6.4

SF3A2

7.2

LOC126075

6.8

GPR89A

6.5

LOC644663

6.5

UNQ470

7.2

TNFRSF7

6.9

LOC129293

6.5

C15orf37

6.5

C6orf21

7.3

LEF1

6.9

CPNE3

6.5

MAL

6.6

CD96

7.3

HLA-DOA

6.9

LY9

6.5

LOC644445

6.6

CD244

7.4

LOC646279

7.0

PIP3-E

6.6

LOC126075

6.6

N/A

7.4

YLPM1

7.0

TAF9

6.6

1-Sep

6.6

KLRK1

7.4

LOC643514

7.0

N/A

6.6

UBASH3A

6.6

C16orf5

7.5

MTMR1

7.0

KIAA0748

6.7

SAA3P

6.6

TRBC1

7.6

NOG

7.1

CD55

6.8

CD6

6.6

LOC339778

7.7

TCF7

7.2

EIF3S6

6.8

TRBV5-4

6.7

GNLY

7.7

KIAA0748

7.2

PGRMC2

6.9

1-Sep

6.7

LDLRAP1

7.7

C21orf7

7.3

C21orf7

6.9

LOC129293

6.8

HAND1

7.7

PRDM9

7.4

PSMD6

7.0

SCNN1D

6.8

CD3D

7.7

FCER2

7.5

ABLIM1

7.0

SIT1

6.8

FLJ45825

7.9

CD8B

7.6

STAG2

7.1

GATA3

6.8

SF3A2

8.0

LEF1

7.8

CCDC45

7.1

CD7

6.8

CXCR3

7.8

UNQ470

7.1

CDKN3

6.8

KIR3DL3

7.9

LY9

7.2

SCAP1

6.8

LAT

8.0

CD40LG

7.3

TRA@

6.9

CD52

7.3

LY9

6.9

TNFRSF7

7.3

DDAH1

6.9

LOC442726

7.3

TRA@

6.9

3-Sep

7.5

TNFRSF7

6.9

KIAA0748

7.5

KIAA0748

6.9

XG

7.6

ITM2A

6.9

KIAA1549

7.6

CD5

7.0

RNF157

7.6

D4S234E

7.0

SIT1

7.6

CD300E

7.0

CD1C

7.7

APBB1

7.0

SLC16A10

7.8

CD3D

7.0

CD3G

7.8

LCK

7.1

CD6

7.8

UBASH3A

7.1

LY9

7.9

XG

7.1

FLT3LG

7.1

LOC647353

7.2

LOC123876

7.2

CX3CR1

7.2

LOC126075

7.3

NELL2

7.4

LY9

7.4

MAL

7.4

KIR2DS2

7.4

CHIA

7.4

BIN1

7.5

CCDC78

7.5

MAL

7.5

C21orf7

7.5

KIR2DL4

7.6

CD6

7.6

CD3D

7.7

1-Sep

7.7

LCK

7.8

ITM2A

7.8

TRA@

7.9

SIT1

7.9

CD5

8.0

CD8A

8.0

LOC129293