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Table 3 Optimal cut-off value of oxy-Hb, rSO 2 , Hb, and base excess at hospital arrival for predicting a good neurologic outcome at 90 days

From: Estimated cerebral oxyhemoglobin as a useful indicator of neuroprotection in patients with post-cardiac arrest syndrome: a prospective, multicenter observational study

Variables

Optimal cut-off

AUC (95% CIs)

Sensitivity (95% CIs)

Specificity (95% CIs)

PPV

NPV

P value ( versus Oxy-Hb)

Oxy-Hb

5.5

0.87 (0.83 – 0.91)

77.3% (72.4 – 82.1)

85.0% (83.2 – 86.7)

47.9%

95.4%

N/A

rSO2

40%

0.83 (0.78 – 0.88)

80.0% (75.3 – 84.6)

78.6% (76.5 – 80.6)

40.0%

95.6%

< 0.001

Hb

13.0 g/dl

0.77 (0.70 – 0.81)

73.3% (68.1 – 78.4)

70.2% (69.7 – 72.4)

30.5%

93.6%

< 0.001

Base excess

−18.7 mM

0.68 (0.63 – 0.74)

96.0% (93.7 – 98.2)

37.4% (35.0 – 39.7)

21.4%

98.1%

< 0.001

  1. AUC, area under the curve; CI, confidence interval; Hb, hemoglobin, NPV, negative predictive value; Oxy-Hb, oxyhemoglobin; PPV, positive predictive value; rSO2, regional cerebral oxygen saturation.
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