Day 90 neurological outcome following ICU admission. The figure represents the day-90 neurological outcome after ICU admission in severely brain-injured patients in the control group (blood glucose range between 5.5 and 9 mmol.L−1) and the intensive insulin therapy (IIT) group (blood glucose range between 4.4 and 6 mmol.L−1). Good neurological outcome is classified as a Glasgow outcome scale (GOS) score of 1 to 2 (good recovery, moderate disability). Poor neurological outcome is classified as a GOS score of 3, 4 or 5 (severe disability, vegetative state, death). χ2 test.