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Table 1 Peak inspiratory airway pressure, applied positive end-expiratory airway pressure, breathing pattern and timing on various modes of mechanical ventilation a

From: Positive end-expiratory airway pressure does not aggravate ventilator-induced diaphragmatic dysfunction in rabbits

Control

CPAP

CPAP-8

AMV

AMV-8

CMV

CMV-8

Peak inspiratory airway pressure (cmH2O) above PEEP

−0.8 ± 0.2

3.2 ± 0.3

3.7 ± 0.6

8.2 ± 0.3b

7.7 ± 0.3b

8.1 ± 0.2b

7.4 ± 0.3b

Applied positive end-expiratory airway pressure (cmH2O)

N/A

N/A

8.3 ± 0.2

N/A

8.1 ± 0.1

N/A

8.4 ± 0.3

Tidal volume (ml/kg)

3.6 ± 0.1b

5.8 ± 0.6

6.4 ± 0.6

7.5 ± 0.3

7.4 ± 0.5

7.5 ± 0.4

5.1 ± 0.2c

Respiratory frequency (breaths/min)

51.6 ± 4.8b

36.6 ± 2.2

29.8 2.8

30.4 ± 2.9

28.7 ± 2.9

40.1 ± 0.1

40.0 ± 0.1

Minute ventilation (L/min)

0.6 ± 0.1

0.8 ± 0.1

0.7 ± 0.1

0.8 ± 0.1

0.7 ± 0.1

1.2 ± 0.1c

0.7 ± 0.0

Inspiratory time (seconds)

0.40 ± 0.04

0.58 ± 0.02c

0.51 ± 0.03

0.47 ± 0.01

0.48 ± 0.01

0.48 ± 0.01

0.47 ± 0.01

Duty cycle

0.35 ± 0.07

0.35 ± 0.02

0.25 ± 0.03

0.24 ± 0.02

0.23 ± 0.03

0.32 ± 0.01

0.32 ± 0.01

  1. aValues are mean ± SE average of those after 1 and 2 days of various modes of mechanical ventilation (n = 6 animals in each group). AMV, Assist-control mechanical ventilation; CMV, Controlled mechanical ventilation (numerical value of 8 next to the ventilatory mode denotes the set CPAP or PEEP of 8 cmH2O); CPAP, Continuous positive airway pressure; N/A, Not applicable; PEEP, Positive end-expiratory airway pressure; VT, Tidal volume. Peak inspiratory airway pressure: bP < 0.01 compared with CPAP and CPAP-8; VT: bP < 0.01 compared with CPAP, CPAP-8, AMV, AMV-8 and CMV. cP < 0.05 compared with CMV, AMV-8 and AMV. Respiratory frequency: bP < 0.01 compared with CPAP, CPAP-8, AMV and AMV-8. Total minute ventilation: cP < 0.05 compared with control, CPAP-8, AMV-8 and CMV-8. Ti: cP < 0.05 compared with control, AMV, AMV-8, CMV and CMV-8.