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Table 2 Patient characteristics by AKI status among ICU patients surviving to hospital discharge, Northern Denmark, 2005 to 2010

From: Three-year risk of cardiovascular disease among intensive care patients with acute kidney injury: a population-based cohort study

  Without AKI AKI stage 1 AKI stages 2-3
  n = 16,764 n = 2,666 n = 2,126
Age    
Age, median (IQR) 57 (39-69) 68 (58-77) 67 (56-75)
Gender    
Female 7,788 (46.5) 1,031 (38.7) 944 (44.4)
Male 8,976 (53.5) 1,635 (61.3) 1,182 (55.6)
Comorbidity    
Ischemic heart disease except MIa 1,863 (11.1) 513 (19.2) 244 (11.5)
Cerebrovascular disease except strokeb 537 (3.2) 124 (4.7) 86 (4.0)
Diabetes 1,490 (8.9) 460 (17.3) 433 (20.4)
Chronic kidney disease 1,063 (6.3) 502 (18.8) 338 (15.9)
Hypertension 2,216 (13.2) 664 (24.9) 511 (24.0)
Peripheral vascular disease 721 (4.3) 266 (10.0) 202 (9.5)
Cancer 2,282 (13.6) 522 (19.6) 375 (17.6)
No surgery 6,455 (38.5) 662 (24.8) 793 (37.3)
Surgery    
Acute cardiac surgery 195 (1.2) 88 (3.3) 59 (2.8)
Acute noncardiac surgery 5,558 (33.2) 834 (31.3) 764 (35.9)
Elective cardiac surgery 1,701 (10.1) 528 (19.8) 169 (7.9)
Elective noncardiac surgery 2,855 (17.0) 554 (20.8) 341 (16.0)
Preadmission drug use    
ACE inhibitors/AT2 antagonists 2,677 (16.0) 763 (28.6) 698 (32.8)
Beta blockers 2,318 (13.8) 667 (25.0) 487 (22.9)
Calcium channel antagonists 1,587 (9.5) 483 (18.1) 401 (18.9)
Acetylsalicylic acid 5,286 (31.5) 1,362 (51.1) 1,005 (47.3)
Diuretics 1,348 (8.0) 357 (13.4) 272 (12.8)
Nitrates 756 (4.5) 236 (8.9) 83 (3.9)
Statins 2,533 (15.1) 671 (25.2) 441 (20.7)
NSAIDs 2,486 (14.8) 430 (16.1) 436 (20.5)
Primary diagnosis during current hospitalization    
Infectious diseases 1,673 (10.0) 276 (10.4) 434 (20.4)
Endocrine diseases 302 (1.8) 69 (2.6) 99 (4.7)
Cardiovascular diseases 2,910 (17.4) 873 (32.7) 390 (18.3)
Respiratory diseases 741 (4.4) 118 (4.4) 108 (5.1)
Gastrointestinal or liver diseases 1,564 (9.3) 287 (10.8) 303 (14.3)
Cancer or other neoplasm 2,463 (14.7) 471 (17.7) 304 (14.3)
Trauma or poisoning 4,198 (25.0) 282 (10.6) 190 (8.9)
Other 2,913 (17.4) 290 (10.9) 298 (14.0)
Laboratory information    
Measured baseline creatinine 10,213 (60.9) 2,143 (80.4) 1,610 (75.7)
Maximum creatinine during admission,c μmol/l, mean (IQR) 74 (62-88) 123 (101-149) 254 (180-397)
ICU treatments    
Mechanical ventilation 4,362 (26.0) 1,297 (48.6) 1,126 (53.0)
Inotropes/vasopressors 3,083 (18.4) 1,158 (43.4) 1,155 (52.9)
Length of admission    
In-hospital daysd, median (IQR) 8 (3-15) 15 (10-28) 23 (12-45)
  1. Values are expressed as number (percentage) unless otherwise indicated. aPatients with a previous diagnosis of myocardial infarction were not included in the study; bpatients with a previous diagnosis of stroke were not included in the study; cfrom ICU admission until hospital discharge; dfrom hospital admission to hospital discharge. If date of discharge from one department and/or hospital and admission to another department and/or hospital was ≤1 calendar day, this was considered as one hospital admission. ACE, angiotensin-converting enzyme; AKI, acute kidney injury; AT2, angiotensin 2; ICU, intensive care unit; IQR interquartile range; n, number; NSAIDS, nonsteroidal anti-inflammatory drugs.