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Figure 3 | Critical Care

Figure 3

From: Renal effects of treatment with a TLR4 inhibitor in conscious septic sheep

Figure 3

Changes in renal artery blood flow (RBF) (A), laser Doppler changes in renal cortex (LD Cortex) (B), laser Doppler changes in renal medulla (LD Medulla) (C), renal vascular resistance (RVR) (D), lactate/pyruvate ratio in cortex (L/P Cortex) (E), and lactate/pyruvate ratio in medulla (L/P Medulla) (F) in response to sepsis and treatment with either the selective TLR4 inhibitor TAK-242 (n = 7) or vehicle (n = 7). Data are expressed as mean and 95% confidence interval. Asterisk indicates a significant difference between TAK-242 and control in response to sepsis. Analysis of variance (ANOVA) repeated measures from 12 to 36 hours.

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