Figure 1
From: Renal effects of treatment with a TLR4 inhibitor in conscious septic sheep
Changes in cardiac index (A), heart rate (B), mean pulmonary arterial pressure (MPAP) (C), arterial lactate (D), mean arterial blood pressure (MAP) (E), and systemic vascular resistance (SVR) (F) in response to sepsis and treatment with either the selective TLR4 inhibitor TAK-242 (n = 7) or vehicle (n = 7). Data are expressed as mean and 95% confidence interval. Asterisk indicates a significant difference between TAK-242 and control in response to sepsis. Analysis of variance (ANOVA) repeated measures from 12 to 36 hours.