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Table 1 Baseline clinical characteristics of subarachnoid hemorrhage patients with versus without left ventricular dysfunction following Takotsubo cardiomyopathy a

From: Impact of transpulmonary thermodilution-based cardiac contractility and extravascular lung water measurements on clinical outcome of patients with Takotsubo cardiomyopathy after subarachnoid hemorrhage: a retrospective observational study

Variable LVEF ≥40% (n = 26) LVEF <40% (n = 20) P-value
Age, yr 67 (55 to 75) 65 (49 to 73) 0.50
Sex, females/males 18/8 14/6 0.61
WFNS grade    
 I to III 13 (50%) 3 (15%) 0.014*
 IV or V 13 (50%) 17 (85%)  
Modified Fisher CT grade    
 2 3 (12%) 2 (10%) 0.98
 3 17 (65%) 13 (65%)  
 4 6 (23%) 5 (25%)  
Aneurysm location    
 Anterior circulation 14 (54%) 9 (45%) 0.38
 Posterior circulation 12 (46%) 11 (55%)  
Treatment    
 Clipping 16 (62%) 8 (40%) 0.13
 Coiling 10 (38%) 12 (60%)  
Blood biochemical marker    
 Cardiac troponin T, ng/ml 0.6 (0.05 to 0.98) 1.1 (0.2 to 1.9) 0.08
 Adrenaline, ng/ml 0.10 (0.03 to 0.14) 0.16 (0.09 to 0.33) 0.08
 Noradrenaline, ng/ml 0.67 (0.26 to 1.15) 0.94 (0.39 to 1.52) 0.15
 Brain natriuretic peptide, pg/ml 82 (32 to 130) 115 (42 to 192) 0.12
LVEF, % 44 (40 to 48) 33 (28 to 37) 0.024*
Cardiopulmonary complication    
 Hypotension <90 mmHg 2 (8%) 4 (20%) 0.21
 Pulmonary edema 4 (15%) 10 (50%) 0.011*
  1. aCT: Computed tomography; LVEF: Left ventricular ejection fraction; WFNS: World Federation of Neurological Surgeons. Numerical variables are presented as median (interquartile range). Categorical variables are expressed as counts (percentage). Numerical variables were analyzed by Mann–Whitney U test or unpaired Student’s t-test. Categorical variables were analyzed by χ2 test or Fisher’s exact test. *Significant P-values.