Figure 2

Achievement of pharmacokinetic/pharmacodynamic targets in intensive care unit patients according to antibiotics used. Data are expressed as percentage of patients achieving target. Doses for each antibiotic are given as a median. This figure was drawn from data in Table 3 of [5] with permission from Oxford Journals. 50% fT > MIC, free drug concentration maintained above minimum inhibitory concentration of the known or suspected pathogen for at least 50% of dosing interval; 50% fT > 4 × MIC, free drug concentration maintained above a concentration fourfold higher than the minimum inhibitory concentration of the known or suspected pathogen for at least 50% of dosing interval; 100% fT > MIC, free drug concentration maintained above minimum inhibitory concentration of the known or suspected pathogen throughout the entire dosing interval; 100% fT > 4 × MIC, free drug concentration maintained above a concentration fourfold higher than the minimum inhibitory concentration of the known or suspected pathogen throughout the entire dosing interval.