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Table 2 Blood gas analysis at Baseline-ZEEP and End

From: Effects of sigh during pressure control and pressure support ventilation in pulmonary and extrapulmonary mild acute lung injury

   ALIp ALIexp
   PCV PSV PCV PSV
   NS Sigh NS Sigh NS Sigh NS Sigh
pHa Baseline-ZEEP 7.26 ± 0.05 7.28 ± 0.07 7.30 ± 0.04 7.28 ± 0.04 7.20 ± 0.13 7.18 ± 0.06 7.21 ± 0.05 7.27 ± 0.05
End 7.25 ± 0.06 7.32 ± 0.05 7.26 ± 0.04 7.21 ± 0.08 7.25 ± 0.07 7.20 ± 0.09 7.25 ± 0.08 7.21 ± 0.11
PaCO2 (mmHg) Baseline-ZEEP 47.3 ± 17.9 43.4 ± 5.2 45.4 ± 3.7 45.8 ± 4.3 49.2 ± 4.6 46.7 ± 7.9 44.6 ± 10.4 44.7 ± 11.7
End 38.6 ± 14.2 45.3 ± 5.4 51.7 ± 3.3 58.7 ± 7.3 43.5 ± 5.0 38.2 ± 3.0 50.3 ± 8.9 52.8 ± 9.2
PaO2 (mmHg) Baseline-ZEEP 151.8 ± 54.4 136.3 ± 56.7 143.6 ± 33.3 125.7 ± 19.5 126.0 ± 24.6 154.3 ± 38.3 132.8 ± 12.1 134.6 ± 38.8
End 386.4 ± 91.5 474.7 ± 114.6 409.5 ± 141.7 430.0 ± 169.7 390.2 ± 158.6 468.8 ± 100 437.7 ± 145.2 424.8 ± 127.5
  1. Values are mean + standard deviation (SD) of six rats in each group. Arterial oxygen partial pressure (PaO2, mmHg), arterial carbon dioxide partial pressure (PaCO2), and arterial pH (pHa) measured at Baseline-ZEEP (zero end-expiratory pressure) and after 1 hour of mechanical ventilation (End) at fraction of inspired oxygen (FiO2) = 1.0 in animals with experimentally induced pulmonary (p) and extrapulmonary (exp) acute lung injury (ALI). ALIp, pulmonary acute lung injury; ALIexp, extrapulmonary acute lung injury; PCV, pressure-controlled ventilation; PSV, pressure support ventilation; NS, non-Sigh.