Figure 1

Time scale of the experimental protocol. In the primary experimental protocol, a sepsis survival program was designed in apolipoprotein E-deficient mice fed a high-fat diet prior to the surgical intervention. In the secondary acute model, the wild-type mice were fed a regular diet until the time of surgery. CCL2, Chemokine (C-C motif) ligand 2; ICAM-1, Intercellular adhesion molecule 1; IL, Interleukin; MCP-1, Monocyte chemotactic protein 1; TNF-α, Tumor necrosis factor α; VCAM-1, Vascular cell adhesion molecule 1.