Table 4 Evolution of blood parameters at 0, 6, 12, and 24 hours after initiation of shock treatment expressed as mean (SEM)

Leukocytes, mm^-3

HSL

6,217 (854)

5,600 (566)

6,665 (698)

7,100 (764)

0.862

0.001

0.844

RL

6,000 (755)

5,805 (842)

6,623 (816)

7,864 (1,016)

Thrombocytes, mm^-3

HSL

47,042 (7,693)

44,583 (6,102)

40,348 (6,001)

48,773 (5,817)

0.297

0.016

0.529

RL

59,409 (7,421)

48,727 (5,870)

50,455 (6,583)

55,909 (4,867)

pH (venous)

HSL

7.40 (0.03)

7.50 (0.01)

7.50 (0.02)

7.46 (0.01)

<0.0001

<0.0001

0.100

RL

7.37 (0.02)

7.40 (0.01)

7.41 (0.01)

7.39 (0.01)

CO₃H^- (venous), mM

HSL

15.20 (0.87)

21.56 (1.04)

26.53 (1.19)

25.18 (0.73)

<0.0001

<0.0001

<0.0001

RL

13.76 (0.72)

15.21 (0.86)

16.94 (0.72)

19.35 (0.85)

Na, mM

HSL

129.8 (1.2)

129.8 (1.2)

130.0 (1.3)

130.6 (1.3)

0.935

0.013

0.081

RL

128.1 (0.9)

129.0 (1.0)

130.3 (0.8)

132.7 (1.3)

K, mM

HSL

4.36 (0.14)

3.42 (0.13)

3.23 (0.11)

3.18 (0.11)

<0.0001

<0.0001

0.001

RL

4.64 (0.17)

4.26 (0.10)

4.23 (0.16)

4.28 (0.15)

Cl, mM

HSL

94.3 (1.3)

90.5 (1.2)

89.5 (1.5)

92.5 (1.1)

<0.0001

0.003

<0.0001

RL

95.8 (1.1)

97.6 (1.0)

99.6 (1.1)

100.9 (0.9)

Osmolality, mOsm/Kg H₂O

HSL

284.0 (4.6)

277.9 (2.2)

278.5 (2.6)

276.4 (2.2)

0.240

0.416

0.104

RL

275.4 (1.8)

274.2 (2.4)

275.2 (1.5)

279.5 (2.6)

Glucose, mM

HSL

6.74 (0.37)

6.56 (0.27)

6.60 (0.39)

5.72 (0.35)

0.003

0.001

0.355

RL

6.11 (0.43)

5.14 (0.27)

5.35 (0.33)

4.85 (0.29)

Lactate, mM

HSL

4.71 (0.67)

2.94 (0.41)

2.93 (0.32)

1.65 (0.20)

0.313

<0.0001

0.183

RL

3.81 (0.85)

1.87 (0.30)

2.11 (0.44)

2.24 (0.54)

Creatinine, mg/dl

HSL

0.677 (0.063)

0.569 (0.066)

0.631 (0.088)

0.607 (0.105)

0.070

<0.0001

0.552

RL

0.549 (0.039)

0.440 (0.023)

0.466 (0.030)

0.416 (0.023)

Albumin, g/L

HSL

32.8 (1.6)

29.5 (1.1)

28.5 (1.1)

26.5 (0.9)

0.695

<0.0001

0.287

RL

34.5 (1.4)

28.5 (0.8)

28.5 (0.7)

27.6 (0.9)

Protein, g/L

HSL

59.3 (2.4)

50.7 (2.3)

48.5 (2.6)

48.0 (1.8)

0.264

<0.0001

0.990

RL

62.2 (2.9)

53.1 (1.8)

51.3 (1.3)

50.2 (1.6)

SGOT u/L

HSL

798 (422)

870 (383)

765 (373)

503 (191)

0.636

0.776

0.263

RL

387 (106)

512 (229)

631 (363)

656 (355)

SGPT u.L^-1

HSL

283 (158)

258 (103)

245 (109)

185 (76)

0.678

0.934

0.267

RL

118 (27)

181 (87)

218 (122)

229 (119)

PT, seconds

HSL

12.0 (0.7)

12.2 (0.8)

12.2 (0.6)

11.4 (0.5)

0.443

0.221

0.094

RL

11.5 (0.7)

11.4 (1.0)

13.6 (2.8)

17.8 (4.6)

aPTT, seconds

HSL

42.0 (4.5)

49.4 (4.7)

50.6 (4.8)

39.9 (2.3)

0.179

0.386

0.117

RL

36.6 (2.4)

39.9 (2.5)

38.3 (3.4)

44.6 (7.9)

Fibrinogen, mg/L

HSL

163.7 (14.6)

123.1 (10.9)

131.7 (11.1)

124.1 (7.2)

0.443

<0.0001

0.734

RL

154.2 (16.7)

117.6 (8.8)

110.5 (7.9)

118.4 (9.6)