Emergent severe acute respiratory distress syndrome caused by adenovirus type 55 in immunocompetent adults in 2013: a prospective observational study

Table 4 Oxygenation response to venovenous extracorporeal membrane oxygenation support ^a

Patient	Conventional ventilation settings pre-ECMO				Pre-ECMO arterial blood gas analysis				Mechanical ventilation settings post-ECMO				Post-ECMO arterial blood gas analysis
Patient	Ventilator type	P_i/PS (cmH₂O)	PEEP (cmH₂O)	FiO₂(%)	pH	PaCO₂(mmHg)	PaO₂(mmHg)	SpO₂(%)	Ventilator type	PS (cmH₂O)	PEEP (cmH₂O)	FiO₂(%)	pH	PaCO₂(mmHg)	PaO₂(mmHg)	SpO₂(%)
Patient 1: ECMO manufacturer/model (4,150 rpm; MAQUET (Wayne, NJ, USA)), 5.2 L/min, 6.8 L/min, total of 8 days on ECMO
	PSV	12	20	1	7.229	62.3	76.7	65	PA/C	10	20	0.3	7.406	37.5	74.7	93
Patient 2: No ECMO, HFOV = 4 Hz, △P = 70 cmH₂O, P_aw = 45 cmH₂O
	PA/C	18	10	0.8	7.267	81	76.3	94	No	–	–	–	–	–	–	–
Patient 3: ECMO manufacturer/model (3,950 rpm; MAQUET (Wayne, NJ, USA)), 5.0 L/min, 5.0 L/min, total of 6 days on ECMO
	PA/C	12	20	1	7.25	66.4	75.4	90	PA/C	10	18	0.4	7.517	41.2	71.5	96
	HFOV = 4.5 Hz, △P = 65 cmH₂O, P_aw = 26 cmH₂O
Patient 4: ECMO manufacturer/model (3,740 rpm; MAQUET (Wayne, NJ, USA)), 4.38 L/min, 4.0 L/min, total of 2 days on ECMO
	SIMV	24	10	1	7.44	38	44	76	PA/C	10	14	0.35	7.441	37.5	89.6	96.8
Patient 5: ECMO manufacturer/model (3,340 rpm; MAQUET (Wayne, NJ, USA)), 4.9 L/min, 4.5 L/min, total of 13 days on ECMO
	PA/C	16	18	1	7.347	74.2	80.2	83	PA/C	12	14	0.3	7.485	40.8	103	96
	HFOV = 4 Hz, △P = 65 cmH₂O, P_aw = 30 cmH₂O

^aECMO, Extracorporeal membrane oxygenation; FiO₂, Fraction of inspired oxygen; HFOV, High-frequency oscillatory ventilation; PA/C, Pressure assist/control; PaCO₂, Partial pressure of carbon dioxide; PaO₂, Partial pressure of oxygen; P_aw, Airway pressure; PEEP, Positive end-expiratory pressure; P_i, Initial pressure; PS, Sustained pressure; PSV, Pressure support ventilation; SIMV, Synchronized intermittent mechanical ventilation; SpO₂, Peripheral capillary oxygen saturation; rpm, rounds per minute. The two liters per minute means the range of blood flow provided at the pump rounds level of ECMO.