Table 1 Differential diagnosis of thrombocytopenia in the ICU
From: Heparin-induced thrombocytopenia in the ICU: an overview
Sepsis and healthcare-associated infections |
Drug-induced thrombocytopenia: e.g., GP IIb/IIIa inhibitor, thrombolytic agents, and antibiotics (e.g., vancomycin) |
Perioperative fluid resuscitation |
Disseminated intravascular coagulation (DIC) |
Massive transfusion |
Intravascular devices: ECMO, IABP, LVAD and pulmonary catheter |
Liver disease/hypersplenism |
Pulmonary embolism |
Immune thrombocytopenias |
Diabetic ketoacidosis |
Cancer-associated DIC, primary bone marrow disorder |
Antiphospholipid syndrome and systemic lupus erythematosis |
EDTA-induced pseudothrombocytopenia |