Long-term outcome in medical patients aged 80 or over following admission to an intensive care unit

Table 2 Characteristics of hospital survivors and factors associated with mortality at 2 years

	Hospital survivors	Two-year survivors	Two-year non-survivors	HR univariate [95% CI]	Punivariate	Adjusted HR [95% CI]	Pmultivariate
Number	133	63	70
Age in years, mean ± SD	84 ± 4	84 ± 4	84 ± 3	1.00 [0.94; 1.08]	0.84
Males	58 (44)	31(49)	27 (39)	1.37 [0.84; 2.23]	0.21
Mechanically ventilated	48 (36)	27 (42)	21 (30)	1.53 [0.93; 2.50]	0.09
Renal replacement therapy	2 (1)	1 (1)	1 (1)	0.72 [0.09; 5.20]	0.75
SAPS II, mean ± SD	42 ± 13	40 ± 13	44 ± 12	1.02 [0.99; 1.03]	0.06	1.02 [1.00; 1.04]	0.03
SOFA score, mean ± SD	4 ± 3	4 ± 3	4 ± 3	1.02 [0.94; 1.11]	0.6
McCabe score					0.029		0.018
No fatal disease	69 (52)	39 (62)	30 (43)	1		1
Fatal disease at 5 years	53 (40)	22 (35)	31 (44)	1.62 [0.96; 2.73]	0.07	1.81 [1.06; 3.13]	0.03
Fatal disease at 1 year	11 (8)	1 (2)	10 (14)	2.60 [1.22; 5.54]	0.013	2.62 [1.23; 5.59]	0.013
Knaus score					0.38
No limitation	27 (20)	9 (14)	18 (26)	1
Slight limitation	53 (40)	26 (41)	27 (39)	1.54 [0.72; 3.30]	0.26
Severe limitation	42 (32)	23 (36)	21 (30)	1.86 [0.86; 4.01]	0.11
Bedridden	11 (8)	6 (10)	5 (7)	2.13 [0.76; 6.00]	0.15
Karnofsky score, category	80 (60-90)	80 (50-90)	80 (50-90)	0.99 [0.98; 1.00]	0.35
Nosocomial pneumonia	7 (5)	3 (5)	4 (6)	0.75 [0.24; 2.39]	0.63
Admission diagnosis					0.43

Data are presented as number (percentage) unless otherwise specified. All variables with a P value of less than 0.2 after univariate analysis were introduced in the multivariate analysis. ^aVersus no fatal disease. CI, confidence interval; HR, hazard ratio; SAPS II, Simplified Acute Physiology Score II; SD, standard deviation; SOFA, Sequential Organ Failure Assessment.

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