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Table 1 Population characteristics and factors associated with hospital mortality

From: Long-term outcome in medical patients aged 80 or over following admission to an intensive care unit

 

All patients

Hospital survivors

Hospital non-survivors

HR univariate [95% CI]

Punivariate

Adjusted HR [95% CI]

Pmultivariate

Number

299

133

166

    

Age in years, mean ± SD

84 ± 4

84 ± 4

84 ± 4

1.02 [0.98; 1.06]

0.35

  

Males

140 (47)

58 (44)

82 (49)

0.90 [0.66; 1.22]

0.51

  

Mechanically ventilated

176 (59)

48 (36)

128 (77)

2.38 [1.65; 3.43]

<0.001

  

Renal replacement therapy

21 (7)

2 (1)

19 (11)

1.54 [0.95; 2.49]

0.08

  

SAPS II, mean ± SD

52 ± 22

42 ± 13

61 ± 24

1.04 [1.03;1.05]

<0.001

1.03 [1.03; 1.04]

<0.001

SOFA score, mean ± SDa

7 ± 4

4 ± 3

8 ± 4

1.18 [1.14; 1.23]

<0.001

  

McCabe score

    

<0.001

 

<0.001

   No fatal disease

129 (43)

69 (52)

60 (36)

1

   

   Fatal disease at 5 years

117 (39)

53 (40)

64 (39)

1.28 [0.90; 1.83]

0.17

1.40 [0.97; 2.02]

0.07b

   Fatal disease at 1 year

53 (18)

11 (8)

42 (25)

2.66 [1.78; 3.96]

<0.001

3.17 [2.08; 4.83]

<0.001b

Knaus score

    

0.04

  

   No limitation

45 (15)

27 (20)

18 (11)

1

   

   Slight limitation

121 (41)

53 (40)

68 (41)

1.51 [0.89; 2.54]

0.12

  

   Severe limitation

103 (34)

42 (32)

61 (37)

1.61 [0.95; 2.73]

0.08

  

   Bedridden

30 (10)

11 (8)

19 (11)

2.55 [1.33; 4.87]

0.004

  

Karnofsky score, median (IQR)

80 (50-90)

80 (60-90)

80 (50-90)

0.99 [0.98; 0.99]

0.03

  

Nosocomial pneumonia

30 (10)

7 (5)

23 (14)

0.77 [0.49; 1.22]

0.27

  

Treatment limitationc

69 (23)

25 (19)

44 (26)

1.38 [0.80-2.05]

0.15

  

Admission diagnosis

    

<0.001

 

0.009

   Respiratory

141 (47)

71 (53)

70 (42)

0.77 [0.51; 1.16]

0.21

0.88 [0.57; 1.34]

0.54

   Coma or neurological

56 (19)

22 (17)

34 (20)

1.23 [0.77; 1.98]

0.39

0.97 [0.59; 1.58]

0.91

   Cardiac

43 (14)

10 (8)

33 (20)

3.04 [1.87; 4.9]

<0.001

2.28 [1.38; 3.77]

<0.001

   Sepsis

29 (10)

12 (9)

17 (10)

1.48 [0.83; 2.6]

0.19

1.32 [0.74; 2.38]

0.35

   Digestive

17 (6)

11 (8)

6 (4)

0.38 [0.16; 0.90]

0.029

0.56 [0.23; 1.35]

0.19

   Renal

7 (2)

3 (2)

4 (2)

0.74 [0.26; 2.12]

0.58

0.46 [0.16; 1.33]

0.15

   Other

6 (2)

4 (2)

2 (1)

0.83 [0.20; 3.39]

0.8

1.51 [0.37; 6.24]

0.57

  1. Data are presented as number (percentage) unless otherwise specified. All variables with a P value of less than 0.2 after univariate analysis were introduced in the multivariate analysis. aSimplified Acute Physiology Score (SAPS II) but not Sequential Organ Failure Assessment (SOFA) score was introduced in the multivariate analysis; bversus no fatal disease; cdecision not to use mechanical ventilation or renal replacement therapy or both. CI, confidence interval; HR, hazard ratio; IQR, interquartile range; SD, standard deviation.