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Table 3 Patient clinical characteristics (three-day ICU)

From: Application and comparison of scoring indices to predict outcomes in patients with healthcare-associated pneumonia

 

All N= 444

Non-ICU N= 333

ICU N= 111

P-value

Survivors N= 351

Non-survivors N= 93

P-value

Clinical features

       

   - Received ventilation

139 (31.3)

45 (13.5)

94 (84.7)

<0.001

87 (24.8)

52 (55.9)

<0.001

   - Septic shock

104 (23.4)

49 (14.7)

55 (49.5)

<0.001

61 (17.4)

43 (46.2)

<0.001

   - Altered mental status

111 (25.0)

53 (15.9)

58 (52.3)

<0.001

66 (18.8)

45 (48.4)

<0.001

   - Pleural effusion

144 (32.4)

97 (29.1)

47 (42.3)

0.010

101 (28.8)

43 (46.2)

0.001

   - Multilobar involvement

242 (54.5)

161 (48.3)

81 (73.0)

<0.001

174 (49.6)

68 (73.1)

<0.001

   - Temperature <35°C or ≥40°C

8 (1.8)

3 (0.9)

5 (4.5)

0.026

3 (0.9)

5 (5.4)

0.012

   - BUN >20 mg/dL

279 (62.8)

191 (57.4)

88 (79.3)

<0.001

206 (58.7)

73 (78.5)

<0.001

   - BUN >30 mg/dL

164 (36.9)

107 (32.1)

57 (51.4)

<0.001

113 (32.2)

51 (54.8)

<0.001

   - Pulse ≥125/minute

97 (21.8)

63 (18.9)

34 (30.6)

0.010

81 (23.1)

16 (17.2)

0.223

   - Respiratory rate >30/minute

31 (7.0)

14 (4.2)

17 (15.3)

<0.001

24 (6.8)

7 (7.5)

0.817

   - Systolic BP <90 mmHg

35 (7.9)

18 (5.4)

17 (15.3)

0.001

21 (6.0)

14 (15.1)

0.004

   - Distolic BP ≤60 mmHg

121 (27.3)

84 (25.2)

37 (33.3)

0.097

87 (24.8)

34 (36.6)

0.023

   - Haematocrit <30%

144 (32.4)

110 (33.0)

34 (30.6)

0.640

105 (29.9)

39 (41.9)

0.028

   - Arterial PH <7.35

65 (14.6)

23 (6.9)

44 (39.6)

<0.001

41 (11.7)

24 (25.8)

0.001

   - Glucose ≥250 mg/dL

44 (9.9)

28 (8.4)

16 (14.4)

0.067

34 (9.7)

10 (10.8)

0.760

   - PaO2 <60 mmHg

86 (19.4)

49 (14.7)

37 (33.3)

<0.001

59 (16.8)

27 (29.0)

0.005

Initial antibiotic therapy§

   

0.583

  

0.001

   - Inadequate

75 (16.9)

57 (17.1)

18 (16.2)

 

52 (14.8)

23 (24.7)

 

   - Adequate

158 (35.6)

162 (48.6)

49 (44.1)

 

117 (33.3)

41 (44.1)

 

   - Indeterminate

211 (47.5)

114 (34.2)

44 (39.6)

 

182 (51.9)

29 (31.2)

 

Outcome

       

   - Length of ICU stay, days

8 (4 to 17)

------

8 (4 to 17)

---

12 (6.5 to 8.5)

8 (2 to 15.3)

0.002

   - Length of hospital stay, days

15 (9 to 25)

15 (8 to 23)

19 (9 to 37)

0.038

17 (9 to 29)

9 (4 to 20)

<0.001

   - In-hospital mortality

117 (26.4)

64 (19.2)

53 (47.8)

<0.001

24 (6.9)

93 (100.0)

<0.001

  1. *Data are expressed as number count (percentage) or median (interquartile range)
  2. §Inadequate initial antibiotic therapy was defined as the condition when the therapy was unable to cover any of the isolated bacterium