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Table 4 Meta-analysis of trials comparing high-frequency ventilation with conventional ventilation: length of ventilation

From: Invasive ventilation modes in children: a systematic review and meta-analysis

Study

CV

HFOV

WMD (95% CI)

Zvalue (Pvalue)

 

Mean (SD)

n

Mean (SD)

n

  

Arnold and colleagues [12]

22 (17)

29

20 (27)

29

2 (-9.61 to 13.61)

-0.338 (0.74)

Dobyns and colleagues [14]

22 (4)

38

52 (28)

12

-30 (-45.89 to -14.11)

3.699 (0.0002)

Subtotal

 

67

 

41

-11.51 (-15.14 to -7.88)

-6.221 (< 0.0001)

Carman and colleagues (VDR) [16]

11 (2)

32

12 (2)

32

-1 (-1.98 to -0.02)

-2.0 (0.046)

Overall

 

99

 

73

-2.34 (-3.63 to -1.04)

-3.542 (0.0004)

  1. CI, confidence interval; CV, conventional ventilation; HFOV, High-frequency oscillation ventilation; SD, standard deviation; VDR, volume diffusive respirator (high-frequency time-cycled pressure ventilator); WMD, weight mean difference.