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Table 4 Meta-analysis of trials comparing high-frequency ventilation with conventional ventilation: length of ventilation

From: Invasive ventilation modes in children: a systematic review and meta-analysis

Study CV HFOV WMD (95% CI) Zvalue (Pvalue)
  Mean (SD) n Mean (SD) n   
Arnold and colleagues [12] 22 (17) 29 20 (27) 29 2 (-9.61 to 13.61) -0.338 (0.74)
Dobyns and colleagues [14] 22 (4) 38 52 (28) 12 -30 (-45.89 to -14.11) 3.699 (0.0002)
Subtotal   67   41 -11.51 (-15.14 to -7.88) -6.221 (< 0.0001)
Carman and colleagues (VDR) [16] 11 (2) 32 12 (2) 32 -1 (-1.98 to -0.02) -2.0 (0.046)
Overall   99   73 -2.34 (-3.63 to -1.04) -3.542 (0.0004)
  1. CI, confidence interval; CV, conventional ventilation; HFOV, High-frequency oscillation ventilation; SD, standard deviation; VDR, volume diffusive respirator (high-frequency time-cycled pressure ventilator); WMD, weight mean difference.