Plasma acetate, gluconate and interleukin-6 profiles during and after cardiopulmonary bypass: a comparison of Plasma-Lyte 148 with a bicarbonate-balanced solution

Table 3 Untransformed acetate, gluconate and interleukin 6 levels according to time of collection

Variable	Fluid		T1	T2	T3	T4
Acetate (mmol/L)	Bicarbonate	mean	0.17	0.49	0.24	0.03
		SD	0.17	0.94	0.23	0.03
		min	0	0.02	0	0
		median	0.13	0.16	0.17	0.03
		max	0.64	3.49	0.81	0.08
	P148	mean	0.21	4.29	0.49	0.03
		SD	0.18	1.76	0.53	0.06
		min	0	2.46	0	0
		median	0.18	3.69	0.35	0
		max	0.54	8.55	1.84	0.23
Gluconate (mmol/L)	Bicarbonate	mean	0.89	1.28	2.13	0.69
		SD	0.54	1.50	1.05	0.38
		min	0.05	0.32	0.88	0.30
		median	0.93	0.75	2.10	0.60
		max	1.70	6.13	3.95	1.82
	P148	mean	1.20	7.44	4.31	1.33
		SD	0.74	1.99	1.18	0.73
		min	0.04	4.92	2.38	0.50
		median	1.07	6.95	3.97	1.18
		max	3.18	12.1	6.51	3.42
IL-6 (pg/mL)	Bicarbonate	mean	1.75	1.88	10.3	72.5
		SD	0.81	0.92	13.4	49.7
		min	0.51	0.74	1.67	12.1
		median	1.69	1.55	7.14	47.9
		max	3.76	3.68	57.2	180
	P148	mean	5.99	4.72	19.2	119
		SD	12.4	8.07	21.4	74.5
		min	1.06	0.89	1.84	29.0
		median	2.65	2.7	12.5	113
		max	50.3	33.6	62.2	309

T1 Immediately before commencing CPB.
T2 Two minutes after commencement of CPB, prior to placement of the aortic cross-clamp.
T3 On rewarming, just prior to separation.
T4 4 hours after separation from CPB.
SD, standard deviation; Min, minimum value; max, maximum value; Bicarbonate, bicarbonate-balanced fluid; P148, Plasma-Lyte 148 fluid.

ISSN: 1364-8535