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Table 2 Randomized controlled trials of selective oropharyngeal decontamination (SOD)a,b

From: Antibiotics or probiotics as preventive measures against ventilator-associated pneumonia: a literature review

Author

n

VAP incidence (versus control) - %

P-value

Mortality (versus control) - %

P-value

Rodriguiz-Roldan [30]

28

0 vs. 73%

< 0.001

30 vs. 33%

NS

Pugin [31]

52

16 vs. 78%

< 0.0001

6 vs. 28%

NS

Laggner [32]

67

3 vs. 12%

NS

27 vs. 41%

NS

Abele-Horn [33]

88

22 vs. 47%

< 0.05

19 vs. 17%

NS

Bergmans [34]

226

10 vs. 23%

0.04

29 vs. 43%

NS

  1. aTrials reporting incidence rates of pneumonia. bAdministration of non-absorbable antibiotics solely in the mouth. VAP, ventilator-associated pneumonia; NS, not significant; -, no data available.
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