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Table 5 Univariate and multivariate analysis of predictive factors of mortality

From: Strategies of initiation and streamlining of antibiotic therapy in 41 French intensive care units

Parameter

OR (95%CI)

Adjusted OR (95%CI)

P-value

Lack of AT protocol

1.4 (0.9 to 2.2)

1.64 (1.01 to 2.69)

0.04

Age ≥60

2.6 (1.6 to 4.1)

1.97 (1.19 to 3.26)

0.008

SAPS II score on admission ≥38

4.5 (2.5 to 7.5)

2.78 (1.60 to 4.84)

<0.0001

Rapidly fatal underlying disease

3.2 (1.8 to 5.8)

2.91 (1.52 to 5.56)

0.001

SOFA score at the beginning of AT ≥6

6.2 (3.5 to 10.9)

4.48 (2.46 to 8.18)

<0.0001

Immunosuppression

1.8 (1.1 to 3.4)

---

0.26

Inappropriate AT

0.6 (0.3 to 1.3)

---

0.19

Septic shock

3.1 (1.9 to 4.9)

---

0.26

University teaching hospitals

0.7 (0.5 to 1.1)

---

0.23

  1. Data are presented in the patients receiving new AT (n = 509). CI, confidence intervals; OR, odds-ratio; Rapidly fatal underlying disease (death <1 year) according to the McCabe score, see material and methods section; SAPS II, simplified acute physiology score II; SOFA, sequential organ failure assessment; AT, antibiotic therapy.
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Critical Care

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