Table 2 Demographic and clinical characteristics of the study subjects
| Â | Healthy controls | Patients with sepsis |
|---|---|---|
Number | 390 | 378 |
Age, years | 65.8 ± 12.2 | 64.1 ± 12.6 |
Males/Females | 226/164 | 220/158 |
APACHE II score | NA | 18.3 ± 4.3 |
Survival | NA | 67.7% |
Length of ICU stay, days | NA | 18.6 ± 5.6 |
Diabetes | NA | 39 (10.3%) |
Chronic liver disease | NA | 12 (3.2%) |
Chronic renal failure | NA | 16 (4.2%) |
Congestive heart failure | NA | 23 (6.1%) |
Chronic pulmonary disease | NA | 31 (8.2%) |
Sepsis insult | Â | Â |
   Lung | NA | 323 (85.4%) |
   Abdomen | NA | 23 (6.1%) |
   Bloodstream | NA | 12 (3.2%) |
   Urinary tract infection | NA | 11 (2.9%) |
   Others | NA | 9 (2.4%) |
Microbiology positive | NA | 159 (42.1%) |
   Gram-positive | NA | 61 (38.4%) |
   Gram-negative | NA | 65 (40.9%) |
   Fungi | NA | 15 (9.4%) |
   Mixed | NA | 18 (11.3%) |
Microbiology unknown | NA | 219 (57.9%) |