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Table 1 Demographic characteristics of patients with pneumonia without organ dysfunction and those with pneumonia-related septic shock

From: Plasma soluble vascular endothelial growth factor receptor-1 levels predict outcomes of pneumonia-related septic shock patients: a prospective observational study

  

Pneumonia with septic shock a

 

Pneumonia without organ dysfunction

Survivors

Non-survivors

P value b

Number of patients

20

38

43

 

Age, years

77.2 (14.1)

79.9 (7.9)

79.7 (11.7)

0.93

Male gender

18 (90%)

32 (84.2%)

37 (86%)

0.81

Comorbidity

    

   Obstructive airway disease

3 (15%)

10 (26.3%)

9 (20.9%)

0.57

   Interstitial lung disease

1 (5%)

6 (15.8%)

5 (11.6%)

0.59

   Congestive heart failure

1 (5%)

5 (13.2%)

4 (9.3%)

0.58

   Diabetes mellitus

6 (30%)

10 (26.3%)

14 (32.6%)

0.54

   Chronic renal insufficiency

1 (5%)

5 (13.2%)

9 (20.9%)

0.36

Pathogens in sputum culture

    

   Gram-positive bacteria

3 (15%)

10 (26.3%)

8 (18.6%)

0.41

   Gram-negative bacteria

3 (15%)

32 (84.2%)

30 (69.8%)

0.12

Pathogens in blood culture

    

   Gram-positive bacteria

0

4 (10.5%)

1 (2.3%)

0.18

   Gram-negative bacteria

0

4 (10.5%)

11 (25.6%)

0.08

Source of pneumonia

   

0.38

   Community-acquired pneumonia

20 (100%)

24 (63.2%)

21 (48.8%)

 

   Hospital-acquired pneumonia

0

7 (18.4%)

9 (20.9%)

 

   Ventilator-acquired pneumonia

0

7 (18.4%)

13 (30.2%)

 

Disease severity

    

   APACHE II score

-

24.1 (5.1)

33.4 (7.1)

<0.001

   PaO2/FiO2 ratio

-

214.2 (87.6)

156.8 (100.3)

<0.001

   Organ dysfunctionc

    

Renal dysfunction

-

10 (26.3%)

28 (65.1%)

<0.001

Hematologic dysfunction

-

7 (18.4%)

20 (46.5%)

0.007

Metabolic acidosis

-

3 (7.9%)

20 (46.5%)

<0.001

Adult respiratory distress syndrome

-

18 (47.4%)

32 (74.4%)

0.012

   Number of organ dysfunctions

    

≥2 organ failures (including shock)

-

23 (60.5%)

39 (90.7%)

0.001

≥3 organ failures (including shock)

-

5 (13.2%)

29 (67.4%)

<0.001

≥4 organ failures (including shock)

-

2 (5.3%)

19 (44.2%)

<0.001

   SOFA score

-

10.6 (2.5)

12.5 (2.6)

<0.001

Hospital length of stay, days

8.4 (3.6)

64.7 (40.5)

22.4 (15.4)

<0.001

Intensive care unit length of stay, days

-

40.6 (25.1)

18.3 (12.0)

<0.001

Combined with other infection sources

-

8 (21.1%)

6 (14%)

0.40

  1. Data are presented as number (percentage), except for age, Acute Physiology and Chronic Health Evaluation II (APACHE II) score, arterial partial pressure of oxygen/fraction of inspired oxygen (PaO2/FiO2) ratio, Sequential Organ Failure Assessment (SOFA) score, hospital length of stay, and intensive care unit length of stay, which are presented as mean (standard deviation). aPatients with pneumonia with septic shock were divided according to survival status at day 28; bP value represents differences between survivors and non-survivors of pneumonia-related septic shock; corgan dysfunction was determined on the day of enrollment.
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Critical Care

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