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Figure 1 | Critical Care

Figure 1

From: Clinical review: Blood purification for sepsis

Figure 1

The 'cytokinetic model'. Blood purification therapies increase the cytokine/chemokine concentration gradient from plasma to infected tissue by removing those inflammatory mediators from the blood compartment. Consequently, leukocyte trafficking is driven toward the nidus of infection, allowing the increase of local bacterial clearance. CPFA, coupled plasma filtration adsorption; HVHF, high-volume hemofiltration.

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Critical Care

ISSN: 1364-8535