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Table 6 Results of first and two consecutive detections of galactomannan in serum of critically ill CORD patients

From: Clinical features of invasive bronchial-pulmonary aspergillosis in critically ill patients with chronic obstructive respiratory diseases: a prospective study

 

Single GM detection (95% CI)

Two consecutive GM detections (95% CI) (n= 48)

 

Positive for a first test ( n = 55)

Positive for a second test ( n = 48)

At least one positive of the two consecutive tests

Both positive for the two consecutive tests

Sensitivity (%)

46.2 (33.3-59.1)

50.0 (35.9-54.1)

53.8 (39.7-67.9)

41.7 (27.8-55.6)

Specificity (%)

83.3 (73.4-93.2)

93.5 (86.5-100)

81.0 (69.9-92.1)

93.5 (86.5-100)

PPV (%)

46.2 (33.3-59.1)

75.0 (62.7-87.3)

46.7 (32.6-60.8)

71.4 (58.7-84.1)

NPV (%)

83.3 (73.4-93.2)

82.9 (72.2-93.6)

85.0 (74.9-95.1)

80.6 (69.7-91.5)

TCR (%)

74.5 (63.0-86.0)

81.4 (70.4-91.4)

74.5 (62.2-86.8)

79.1 (67.9-90.3)

  1. CORD, chronic obstructive respiratory disease; NPV, negative predictive value; PPV, positive predictive value; TCR, total consistent rate.