Figure 3
From: Small airway remodeling in acute respiratory distress syndrome: a study in autopsy lung tissue
Representative photomicrographs of extracellular matrix proteins and matrix metalloproteinase-9 expression in the airways. Photomicrographs of small airways from ARDS patients (A, C, E, G) and controls (B, D, F, H) stained with anti-collagen I (A and B), anti-fibronectin (C and D), anti-versican (E and F) and anti-MMP-9 (G and H). ARDS airways show higher content of collagen I, fibronectin and versican and higher MMP-9 expression by inflammatory cells. L = lumen; SM = smooth muscle; OL = outer layer; IL = inner layer. Scale bars = 50 μm.