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Table 2 Optimal BNP and NT-proBNP cut-point assessed by maximizing the sum between sensitivity and specificity to discriminate between 1-year survivors and non-survivors at different time points

From: Direct comparison of serial B-type natriuretic peptide and NT-proBNP levels for prediction of short- and long-term outcome in acute decompensated heart failure

Natriuretic peptide (NP)

NP value, pg/mL

Sensitivity, percentage

Specificity, percentage

LR+

LR-

BNP at 24 hours

1,223

65

76

2.7

0.46

BNP at 48 hours

1,027

76

71

2.5

0.34

BNP at discharge

921

72

74

2.9

0.37

NT-proBNP at 24 hours

8,229

69

77

3.1

0.39

NT-proBNP at 48 hours

7,617

72

81

3.9

0.34

NT-proBNP at discharge

7,042

61

90

6.7

0.43

  1. BNP, B-type natriuretic peptide; LR+, positive likelihood ratio; LR-, negative likelihood ratio; NT-proBNP, N-terminal B-type natriuretic peptide.
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Critical Care

ISSN: 1364-8535