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Table 1 Lung injury scores after 2 hours of ventilator-induced lung injury (30 mL/kg)

From: Hydrogen inhalation ameliorates ventilator-induced lung injury

   Lung injury score
Group Treatment Alveolar congestion Hemorrhage Infiltration of neutrophils Alveolar wall thickness Total score
Sham N2 0.25 ± 0.50 0 0.50 ± 0.58 0 0.75 ± 0.50
Sham H2 0.25 ± 0.50 0 0.25 ± 0.50 0 0.50 ± 0.58
VILI N2 1.75 ± 0.50 0 1.75 ± 0.96 1.50 ± 0.58 5.0 ± 1.63*
VILI H2 0.75 ± 0.50 0 1.50 ± 0.57 0.75 ± 0.50 3.0 ± 0.82
  1. Data are presented as mean ± standard deviation (* P < 0.05 versus ventilator-induced lung injury [VILI]/N2). Acute lung injury was scored in each sample (n = 6 for each group) according to the following four items: alveolar congestion, hemorrhage, infiltration or aggregation of neutrophils in airspace or the vessel wall, and thickness of the alveolar wall/hyaline membrane formation. Each item was graded according to a 5-point scale: 0, minimal (little) damage; 1, mild damage; 2, moderate damage; 3, severe damage; and 4, maximal damage.