Table 1 Comparison of patients with metformin-associated lactic acidosis with patients with lactic acidosis of other origin

67 ± 13

66 ± 9

67 ± 13

65 ± 13

68 ± 12

73 ± 11

72 ± 9

64 ± 15

56 ± 14

121 (61%)

4 (40%)

117 (63%)

45 (62%)

24 (57%)

26 (67%)

6 (75%)

7 (54%)

9 (69%)

74 ± 20

88 ± 23

73 ± 19^a

81 ± 16

71 ± 19^a

75 ± 18

73 ± 25

54 ± 15^b

54 ± 14^b

12.5 ± 3.6

14.3 ± 1.4

12.4 ± 3.7

12.9 ± 2.9

12.1 ± 4.5

11.8 ± 2.8^b

14.4 ± 4.4

13.4 ± 4.6

9.6 ± 4.2^b

2.5 ± 1.0

2.7 ± 0.9

2.5 ± 1.0

2.7 ± 0.9

2.1 ± 1.3

2.4 ± 0.6

2.6 ± 1.1

2.3 ± 1.5

2.2 ± 1.4

2.4 ± 1.2

4.0 ± 0.0

2.3 ± 1.2^b

2.1 ± 1.2^b

2.5 ± 1.2^b

2.5 ± 1.1^b

2.8 ± 0.8^a

2.1 ± 1.5^b

1.9 ± 1.3^b

0.7 ± 1.0

0.3 ± 0.7

0.7 ± 1.0

0.3 ± 0.6

1.3 ± 1.2^a

0.6 ± 0.8

0.6 ± 0.9

1.8 ± 1.7

0.9 ± 0.9

3.3 ± 1.4

4.0 ± 0.0

3.3 ± 1.5

3.5 ± 1.3

3.2 ± 1.5

3.4 ± 1.5

4.0 ± 0.0

2.9 ± 1.8

2.1 ± 2.0^a

0.9 ± 1.2

0.5 ± 0.8

0.9 ± 1.2

0.6 ± 0.9

1.3 ± 1.4

0.3 ± 0.7

2.2 ± 1.6

2.6 ± 1.1

0.9 ± 1.2

2.7 ± 1.4

2.8 ± 1.5

2.7 ± 1.4

3.7 ± 0.6^a

1.7 ± 1.3^a

2.8 ± 1.2

2.2 ± 1.3

1.8 ± 1.4^b

1.6 ± 1.2

11.6 ± 6.2

18.7 ± 5.3

11.2 ± 6.1^b

12.8 ± 6.1^b

8.7 ± 4.5^b

10.9 ± 5.2^b

8.6 ± 3.3^b

13.5 ± 9.5^b

10.8 ± 7.1^b

7.13 ± 0.19

6.75 ± 0.13

7.15 ± 0.17^b

7.07 ± 0.19^b

7.23 ± 0.09^b

7.18 ± 0.14^b

7.27 ± 0.04^b

7.26 ± 0.07^b

7.14 ± 0.18^b

14.6 ± 5.9

4.4 ± 2.4

15.2 ± 5.6^b

14.5 ± 5.6^b

16.6 ± 5.8^b

14.9 ± 4.0^b

16.2 ± 1.8^b

15.8 ± 5.7^b

14.1 ± 8.8^b

307 ± 265

796 ± 324

227 ± 141^b

169 ± 128^b

318 ± 181^b

182 ± 48^b

299 ± 125^a

303 ± 122^a

214 ± 57^b

52 (26%)

5 (50%)

48 (26%)

19 (26%)

9 (21%)

9 (23%)

0

5 (38%)

6 (46%)