De-escalation as part of a global strategy of empiric antibiotherapy management. A retrospective study in a medico-surgical intensive care unit

Table 6 Multivariate logistic regression analysis to assess factors associated with de-escalation therapy

	OR (95% IC)	P-value
MDR at admission	0.02 (0.00; 0.36)	0.008
Aminoglycoside	18.08 (2.25; 145)	0.006
Monotherapy	0.28 (0.12; 0.63)	0.002
Adequate antibiotic therapy	5.25(1; 27.4)	0.049

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