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Table 5 Empirical antibiotic treatment. Comparison between groups D and ND

From: De-escalation as part of a global strategy of empiric antibiotherapy management. A retrospective study in a medico-surgical intensive care unit

  Group D
n= 60
Group ND
n= 73
P-value
Antibiotic with activity against MSS, n (%) 2 (3.3) 0 0.12
Antibiotic with activity against MRS, n (%) 21 (35) 12 (16.4) 0.01
ß-lactam antibiotic with no activity against nfGNB, n (%) 36 (60) 50 (68.5) 0.31
ß-lactam antibiotic with activity against nfGNB, n (%) 26 (43.3) 27 (37) 0.41
Quinolone (except ciprofloxacin), n (%) 5 (8.3) 8 (11) 0.53
Aminoglycoside, n (%) 20 (32.3) 3 (4.1) <0.0001
Monotherapy, n (%) 14 (23.3) 44 (60.3) <0.001
More than two antibiotics, n (%) 19 (31.7) 4 (5.4) 0.002
  1. MRS, methicillin-resistant staphylococcus; MSS, methicillin-sensible staphylococcus; nfGNB, non fermenting Gram-negative bacilli.