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Table 5 Empirical antibiotic treatment. Comparison between groups D and ND

From: De-escalation as part of a global strategy of empiric antibiotherapy management. A retrospective study in a medico-surgical intensive care unit

 

Group D

n= 60

Group ND

n= 73

P-value

Antibiotic with activity against MSS, n (%)

2 (3.3)

0

0.12

Antibiotic with activity against MRS, n (%)

21 (35)

12 (16.4)

0.01

ß-lactam antibiotic with no activity against nfGNB, n (%)

36 (60)

50 (68.5)

0.31

ß-lactam antibiotic with activity against nfGNB, n (%)

26 (43.3)

27 (37)

0.41

Quinolone (except ciprofloxacin), n (%)

5 (8.3)

8 (11)

0.53

Aminoglycoside, n (%)

20 (32.3)

3 (4.1)

<0.0001

Monotherapy, n (%)

14 (23.3)

44 (60.3)

<0.001

More than two antibiotics, n (%)

19 (31.7)

4 (5.4)

0.002

  1. MRS, methicillin-resistant staphylococcus; MSS, methicillin-sensible staphylococcus; nfGNB, non fermenting Gram-negative bacilli.