Skip to main content

Table 3 Per sample sensitivity, specificity, with 95% confidence intervals of Mn, A-Mn and combined Mn/A-Mn testing

From: The use of mannan antigen and anti-mannan antibodies in the diagnosis of invasive candidiasis: recommendations from the Third European Conference on Infections in Leukemia

Study

Mn

A-Mn

Mn/A-Mn

Mn

A-Mn

Mn/A-Mn

Verduyn Lunel, 2009 [31]

0.17 (0.13-0.22),

41/240

0.39 (0.33-0.45),

93/238

-

0.95 (0.92-0.97),

379/390

0.87 (0.83-0.90),

347/384

-

Sendid, 2008 [37]

0.67 (0.55-0.77),

46/69

0.35 (0.25-0.47),

24/69

-

-

-

-

Fujita, 2006 [29]

0.45 (0.39-0.51),

112/251

-

-

0.92 (0.87-0.95),

164/178

  

Sendid et al., 2003 [27]

0.54 (0.43-0.64),

44/82

0.23 (0.15-0.33),

19/82

0.68 (0.58-0.77),

56/82

0.98 (0.89-0.99),

47/48

1 (0.93-1.0),

48/48

0.98 (0.89-0.99),

47/48

Sendid et al., 2002 [17]

0.35 (0.29-0.42),

72/204

0.27 (0.22-0.34),

56/204

0.55 (0.49-0.62),

113/204

-

-

-

Sendid et al., 1999 [16]

0.27 (0.20-0.34), 43/162

0.39 (0.32-0.47), 63/162

0.62 (0.55-0.69), 101/162

0.99 (0.96-0.99), 227/230

0.96 (0.93-0.98), 221/230

0.94 (0.91-0.97),

218/230

Median of all the studies (range)

0.40 (0.17-0.67)

0.35 (0.23-0.39)

0.62 (0.55-0.68)

0.97 (0.92-0.99)

0.96 (0.87-1.0)

0.96 (0.94-0.98)

  1. -, no data.