Figure 1
From: Clinical review: Anticoagulation for continuous renal replacement therapy - heparin or citrate?
Simplification of heparin binding to proteins and cells. Heparins bind to proteins and cells, and thereby interfere with the inflammatory cascade and, altogether, confer unpredictable consequences for critically ill patients. H, heparin; AT, antithrombin; LBP, lipopolysaccharide-binding protein; M, monocyte; MPO, myeloperoxidase; SOD, superoxide dismutase; GAGs, glucosaminoglycans; P, platelet; L, leukocyte.