Parameter | Group | BL = 0 hours | 6 hours | 12 hours | 24 hours |
---|---|---|---|---|---|
Cardiac index (l/min/m2) | Sham | 100 ± 0 | 90.7 ± 2.8 | 86.2 ± 3.0 | 82.5 ± 3.0 |
 | Control | 100 ± 0 | 117.1 ± 10.0 | 122.7 ± 5.9#†| 166.2 ± 16.2#†|
 | rhAPC | 100 ± 0 | 109.6 ± 9.2 | 113.2 ± 6.6*†| 124.2 ± 6.9*†|
Pancreas (%) | Sham | 100 ± 0 | 97.3 ± 10.5 | 94.9 ± 8.1 | 104.0 ± 16.1 |
 | Control | 100 ± 0 | 55.5 ± 9.3 | 60.5 ± 12.3# | 52.3 ± 6.9#†|
 | rhAPC | 100 ± 0 | 76.5 ± 9.5 | 61.3 ± 9.5# | 65.5 ± 15.2# |
Ileum (%) | Sham | 100 ± 0 | 95.4 ± 20.2 | 89.1 ± 11.3 | 111.8 ± 23.5 |
 | Control | 100 ± 0 | 102.4 ± 13.5 | 156.0 ± 38.6#†| 135.1 ± 28.1 |
 | rhAPC | 100 ± 0 | 95.6 ± 9.2 | 107.8 ± 19.0 | 136.0 ± 32.3 |
Medulla oblongata (%) | Sham | 100 ± 0 | 91.3 ± 11.2 | 95.5 ± 8.3 | 93.1 ± 17.1 |
 | Control | 100 ± 0 | 78.1 ± 7.1 | 132.1 ± 17.5 | 145.0 ± 16.7# |
 | rhAPC | 100 ± 0 | 75.3 ± 9.3 | 89.6 ± 22.4 | 97.2 ± 16.9 |
Thalamus (%) | Sham | 100 ± 0 | 92.6 ± 7.4 | 95.2 ± 9.9 | 93.9 ± 13.8 |
 | Control | 100 ± 0 | 90.2 ± 9.3 | 137.0 ± 18.1# | 157.7 ± 31.6# |
 | rhAPC | 100 ± 0 | 96.1 ± 4.8 | 95.8 ± 9.1* | 107.5 ± 10.3* |
Pons (%) | Sham | 100 ± 0 | 95.9 ± 9.9 | 92.6 ± 7.5 | 96.1 ± 18.3 |
 | Control | 100 ± 0 | 87.7 ± 8.8 | 130.0 ± 14.7# | 167.3 ± 26.7#†|
 | rhAPC | 100 ± 0 | 78.1 ± 6.0 | 81.8 ± 9.1* | 104.4 ± 15.5* |