Skip to main content
Figure 4 | Critical Care

Figure 4

From: Temporal increase of platelet mitochondrial respiration is negatively associated with clinical outcome in patients with sepsis

Figure 4

Quantification of mitochondrial DNA (mtDNA) and cytochrome c (Cyt c ) content in platelets. A. Platelet mtDNA content did not change in the septic patients during the first week or compared to controls. B. Cyt c content increased significantly from Day 1 to 2 to Day 6 to 7 in septic patients but not compared to controls. C. Maximal FCCP-titrated respiration (CI + IIETS) adjusted to mtDNA increased similarly as when adjusted to platelet count. D. Maximal respiration (CI + IIETS) adjusted to Cyt c demonstrated an increasing trend but no significant change. Mean values ± SEM, n = 16-18, *P < 0.05 compared to Day 1 to 2, § P < 0.05 compared to controls.

Back to article page

Critical Care

ISSN: 1364-8535