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Table 2 Transpulmonary thermodilution parameters over the study period

From: Validation of a new transpulmonary thermodilution system to assess global end-diastolic volume and extravascular lung water

 

BASE1

DOBU

BASE2

HYPO

BASE3

HYPER

ALI

CO1 (l/min)

7.5 ± 0.9, 7.6 (6.9 to 8.2)

10.8 ± 1.4*, 10.9 (10.0 to 11.5)

7.5 ± 0.7, 7.4 (7.2 to 7.8)

4.7 ± 0.3*, 4.9 (4.5 to 4.9)

7.9 ± 1.2, 7.7 (7.2 to 8.6)

11.7 ± 2.1*, 11.8 (10.1 to 13.1)

6.7 ± 3.3*, 5.2 (4.5 to 8.7)

CO2 (l/min)

7.6 ± 0.8, 7.9 (7.3 to 8.1)

11.0 ± 1.6*, 11.0 (10.1 to 11.7)

7.6 ± 0.8, 7.3 (7.1 to 8.1)

4.8 ± 0.2*, 4.9 (4.6 to 4.9)

8.0 ± 1.2, 8.0 (7.3 to 8.7)

12.0 ± 2.1*, 11.8 (10.5 to 13.5)

6.9 ± 3.4*, 5.7 (4.6 to 9.0)

GEDV1 (ml)

1,077 ± 149, 1,116 (953 to 1,171)

1,059 ± 134, 1,001 (958 to 1,167)

1,110 ± 147, 1,139 (990 to 1,230)

925 ± 84*, 943 (885 to 977)

1,173 ± 120, 1,164 (1,102 to 1,240)

1,326 ± 140*, 1,288 (1,245 to 1,440)

1,070 ± 191*, 1,144 (929 to 1,170)

GEDV2 (ml)

1,052 ± 94, 1,040 (1,009 to 1,076)

1,023 ± 102, 1,038 (942 to 1,056)

1,093 ± 124, 1,117 (1,000 to 1,177)

931 ± 66*, 937 (911 to 978)

1,153 ± 100, 1,157 (1089 to 1,214)

1,299 ± 162*, 1,322 (1,218 to 1,363)

1,089 ± 174*, 1,118 (976 to 1,194)

EVLW1 (ml)

622 ± 86, 627 (558 to 684)

691 ± 112, 650 (631 to 723)**

653 ± 106, 639 (577 to 692)

609 ± 72*, 597 (549 to 675)

644 ± 82, 638 (563 to 710)

754 ± 117, 804 (654 to 858)**

1,587 ± 380, 1,609 (1,305 to 1,711)**

EVLW2 (ml)

621 ± 82, 613 (552 to 683)

642 ± 68, 628 (596 to 666)

635 ± 85, 619 (592 to 678)

624 ± 68, 626 (580 to 679)

624 ± 80, 587 (567 to 710)

749 ± 128*, 750 (654 to 823)

1,571 ± 335*, 1,580 (1,374 to 1,752)

  1. Results are expressed as the mean ± standard deviation, median (interquartile range). CO, cardiac output; GEDV, global end-diastolic volume; EVLW, extravascular lung water; subscript 1, current method (PiCCO™; Pulsion); subscript 2, new method (VolumeView™; Edwards); BASE, baseline; DOBU, dobutamine infusion; HYPO, hypovolemia induced by bleeding; HYPER, hypervolemia induced by volume loading; ALI, acute lung injury induced by oleic acid. *P < 0.01 (DOBU vs. BASE1 or HYPO vs. BASE2 or HYPER vs. BASE3 or ALI vs. HYPER); normal distribution, paired t test. **P < 0.01 (DOBU vs. BASE1 or HYPER vs. BASE3 or ALI vs. HYPER); abnormal distribution, nonparametric paired Wilcoxon signed-rank test. At each stage, values measured with the new VolumeView™ and with the current PiCCO method were comparable.