Figure 4From: Acute pancreatitis with organ dysfunction associates with abnormal blood lymphocyte signaling: controlled laboratory studySTAT3 signaling. Levels of phosphorylated STAT3 (pSTAT3) in lymphocytes of healthy subjects (circles) and patients (quadrangles) in whole blood samples without supplement (open symbols) or supplemented (closed symbols) with IL-6 (100 ng/ml, five minutes). A. Fluorescence intensity (RFU, relative fluorescence units); B. sample histograms; C. proportion of pSTAT3-positive cells among all lymphocytes (N = 12 to 13); D. Fluorescence intensity; E. proportion of pSTAT3-positive lymphocytes among; F. fluorescence intensity of pSTAT3-positive lymphocytes among subsets of non-stimulated lymphocytes. Horizontal lines in A and C-F denote median and M1 (marker) in B denotes proportion of pSTAT3-positive lymphocytes. *P < 0.05, **P < 0.01, *** P < 0.001.Back to article page