|  | No. patients without risk factor (%) | Sensitivity, % (95% CI) | Specificity, % (95% CI) | NPV, % (95% CI) | PPV, % (95% CI) | LR + (95% CI) | LR - (95% CI) |
---|---|---|---|---|---|---|---|---|
Model 1 | Â | Â | Â | Â | Â | Â | Â | Â |
   Risk factor | A | 271 (47) | 70 (62 to 78) | 52 (46 to 56) | 86 (81 to 89) | 30 (25 to 35) | 1.45 (1.25 to 1.68) | 0.58 (0.44 to 0.75) |
   Risk factors | A, B | 127 (22) | 90 (83 to 94) | 25 (21 to 30) | 90 (83 to 94) | 26 (22 to 30) | 1.21 (1.12 to 1.30) | 0.39 (0.23 to 0.66) |
   Risk factors | A, B, C | 112 (19) | 93 (87 to 97) | 23 (19 to 27) | 92 (85 to 96) | 26 (22 to 30) | 1.21 (1.13 to 1.29) | 0.30 (0.16 to 0.57) |
Model 2 | Â | Â | Â | Â | Â | Â | Â | Â |
   Risk factor | B | 270 (46) | 68 (60 to 76) | 51 (46 to 56) | 85 (80 to 89) | 29 (24 to 34) | 1.39 (1.21 to 1.62) | 0.61 (0.48 to 0.80) |
   Risk factors | B, D | 229 (39) | 78 (70 to 85) | 45 (40 to 49) | 88 (83 to 92) | 29 (25 to 34) | 1.42 (1.26 to 1.61) | 0.48 (0.34 to 0.67) |
   Risk factors | P, B | 140 (24) | 97 (92 to 99) | 30 (26 to 34) | 97 (92 to 99) | 29 (25 to 33) | 1.39 (1.30 to 1.49) | 0.10 (0.04 to 0.27) |
   Risk factors | P, B, D | 116 (20) | 97 (92 to 99) | 25 (21 to 29) | 97 (91 to 99) | 27 (23 to 32) | 1.29 (1.21 to 1.37) | 0.12 (0.05 to 0.33) |
Model 3 | Â | Â | Â | Â | Â | Â | Â | Â |
   PCT > 0.25 µg/l |  | 234 (40) | 95 (89 to 98) | 50 (46 to 55) | 97 (94 to 99) | 36 (31 to 41) | 1.91 (1.73 to 2.11) | 0.11 (0.05 to 0.22) |