Predictive value of procalcitonin decrease in patients with severe sepsis: a prospective observational study

Table 2 Procalcitonin concentrations in different patient groups

	Procalcitonin, ng/mL
	Day 0	72 hours
All patients	5.0 (1.0-20.1)	1.3 (0.5-5.8)
Septic shock (SOFA 4)^a	6.5 (1.6-29.0)	2.3 (0.7-7.4)
Without septic shock (SOFA 0-3)^a	3.2 (0.9-14.7)	1.1 (0.3-4.4)
Severe acute kidney injury (SOFA 3-4)^b	9.4 (2.4-38.2)	4.9 (0.9-9.5)
Without severe acute kidney injury (SOFA 0-2)^b	4.3 (0.9-16.4)	1.2 (0.3-4.9)
Blood culture-positive infection^c	15.6 (4.3-43.6)	5.2 (1.7-8.7)
Blood culture-negative infection^c	2.9 (0.8-12.5)	1.0 (0.3-4.3)
Community-acquired infection^d	6.6 (1.4-33.2)	2.4 (0.7-6.5)
Nosocomial infection^d	2.9 (0.8-10.6)	0.9 (0.2-2.8)

The data are presented as median (interquartile range). P values refer to differences between patient groups (for example, those with and those without septic shock). ^aP = 0.020 on day 0 and P = 0.031 at 72 hours; ^bP = 0.027 on day 0 and P = 0.02 at 72 hours; ^cP < 0.001 on day 0 and P < 0.001 at 72 hours; ^dP = 0.001 on day 0 and P = 0.003 at 72 hours. SOFA, Sequential Organ Failure Assessment.

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