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Table 2 Laboratory characteristics of the patients

From: Clinical aspects and cytokine response in severe H1N1 influenza A virus infection

Laboratory characteristic All patients with nvA(H1N1) infection (n= 32) nvA(H1N1)-ARDS group (n= 21) nvA(H1N1)-mild disease group (n= 11) P valuea ARDS bacterial sepsis group (n= 20) P valueb
Leukocyte count (x103/μl) 9.8 (7.5 to 11.8) 9.7 (8 to 12.3) 9.9 (6 to 10.5) 0.41 14.2 (8.2 to 20.5) 0.047
Lymphocyte count (x103/μl) 1.05 (0.7 to 1.87) 0.9 (0.6 to 1.3) 1.6 (0.9 to 2.5) 0.011 1.38 (1.12 to 2.9) 0.009
Platelet count (x103/μl) 218 (180 to 270) 218 (169 to 288) 218 (180 to 270) 0.7 241 (142.8 to 298) 0.8
C-reactive protein (mg/dl) 4.8 (1.2 to 9.6) 5.35 (4 to 10.2) 1.2 (0.6 to 4.4) 0.004 9.8 (5.75 to 22) 0.05
Procalcitonin (ng/ml) 0.23 (0.05 to 0.85) 0.39 (0.11 to 1.12) 0.06 (0.05 to 0.06) 0.003 6.3 (4.6 to 11.5) < 0.001
LDH (IU/l) 698 (360 to 980) 890 (618 to 1134) 360 (250 to 400) < 0.001 547 (408 to 812) 0.07
ALT (IU/l) 30.5 (17 to 80.75) 43 (21 to 92.5) 22 (15 to 30) 0.049 25 (13.5 to 50.75) 0.09
AST (IU/l) 42 (20 to 98) 95 (32.5 to 164) 17 (16 to 28) < 0.001 25 (20 to 656) 0.003
Total protein level (mg/dl) 6.75 (6 to 7.55) 6.2 (5.8 to 7) 8 (7 to 8) < 0.001 5.4 (4.8 to 6.4) 0.015
Creatinine level (mg/dl) 0.96 (0.6 to 1.17) 1.1 (0.9 to 1.25) 0.6 (0.5 to 0.8) < 0.001 1.55 (1 to 2.37) 0.11
  1. Data presented as median (interquartile range). ALT, alanine aminotransferase; ARDS, acute respiratory distress syndrome; AST, aspartate aminotransferase; LDH, lactate dehydrogenase; nvA(H1N1), novel A(H1N1) virus. aComparison between nvA(H1N1)-ARDS and nvA(H1N1)-mild disease (Mann-Whitney U test). bComparison between nvA(H1N1)-ARDS and bacterial sepsis-ARDS (Mann-Whitney U test).