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Table 2 Laboratory characteristics of the patients

From: Clinical aspects and cytokine response in severe H1N1 influenza A virus infection

Laboratory characteristic

All patients with nvA(H1N1) infection (n= 32)

nvA(H1N1)-ARDS group (n= 21)

nvA(H1N1)-mild disease group (n= 11)

P valuea

ARDS bacterial sepsis group (n= 20)

P valueb

Leukocyte count (x103/μl)

9.8 (7.5 to 11.8)

9.7 (8 to 12.3)

9.9 (6 to 10.5)

0.41

14.2 (8.2 to 20.5)

0.047

Lymphocyte count (x103/μl)

1.05 (0.7 to 1.87)

0.9 (0.6 to 1.3)

1.6 (0.9 to 2.5)

0.011

1.38 (1.12 to 2.9)

0.009

Platelet count (x103/μl)

218 (180 to 270)

218 (169 to 288)

218 (180 to 270)

0.7

241 (142.8 to 298)

0.8

C-reactive protein (mg/dl)

4.8 (1.2 to 9.6)

5.35 (4 to 10.2)

1.2 (0.6 to 4.4)

0.004

9.8 (5.75 to 22)

0.05

Procalcitonin (ng/ml)

0.23 (0.05 to 0.85)

0.39 (0.11 to 1.12)

0.06 (0.05 to 0.06)

0.003

6.3 (4.6 to 11.5)

< 0.001

LDH (IU/l)

698 (360 to 980)

890 (618 to 1134)

360 (250 to 400)

< 0.001

547 (408 to 812)

0.07

ALT (IU/l)

30.5 (17 to 80.75)

43 (21 to 92.5)

22 (15 to 30)

0.049

25 (13.5 to 50.75)

0.09

AST (IU/l)

42 (20 to 98)

95 (32.5 to 164)

17 (16 to 28)

< 0.001

25 (20 to 656)

0.003

Total protein level (mg/dl)

6.75 (6 to 7.55)

6.2 (5.8 to 7)

8 (7 to 8)

< 0.001

5.4 (4.8 to 6.4)

0.015

Creatinine level (mg/dl)

0.96 (0.6 to 1.17)

1.1 (0.9 to 1.25)

0.6 (0.5 to 0.8)

< 0.001

1.55 (1 to 2.37)

0.11

  1. Data presented as median (interquartile range). ALT, alanine aminotransferase; ARDS, acute respiratory distress syndrome; AST, aspartate aminotransferase; LDH, lactate dehydrogenase; nvA(H1N1), novel A(H1N1) virus. aComparison between nvA(H1N1)-ARDS and nvA(H1N1)-mild disease (Mann-Whitney U test). bComparison between nvA(H1N1)-ARDS and bacterial sepsis-ARDS (Mann-Whitney U test).