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Figure 1 | Critical Care

Figure 1

From: Clinical review: Prothrombin complex concentrates - evaluation of safety and thrombogenicity

Figure 1

Coagulation factors accumulate differently when a prothrombin complex concentrate is administered repeatedly. Illustration of how coagulation factors accumulate differently when a prothrombin complex concentrate (PCC) is administered repeatedly due to their different half-lives. The example shows the theoretical accumulation of factors in plasma sampled immediately after dosing when 40 units/kg four-factor PCC is given every 12 hours to a 70 kg patient.

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Critical Care

ISSN: 1364-8535