From: Hyperoncotic colloids and acute kidney injury: a meta-analysis of randomized trials
Trial | Indication | Mean age, years | Treatment | AKI criteria |
---|---|---|---|---|
Zetterström and Hedstrand [17], 1981 | Elective major abdominal surgery | 58.5 | Postoperative crystalloid with versus without 20% albumin | At least 70% SCr and urea increase |
Ginès et al. [18], 1988 | Treatment of ascites in hospitalized cirrhotic patients | 57.0 | Paracentesis with versus without 20% albumin | At least 50% SCr or BUN increase to greater than 1.5 or 30 mg/dL, respectively |
London et al. [19], 1989 | CPB surgery | 63.5 | 10% pentastarch versus 5% albumin for first 24 hours postoperatively | Emergency dialysis necessitated by acute renal failure |
GarcÃa-Compeán et al. [20], 1993 | Hospital treatment of tense ascites causing respiratory dysfunction in cirrhotic patients | 55.7 | Total therapeutic paracentesis with versus without 25% albumin | Greater than 50% SCr or BUN increase to greater than 1.5 mg/dL or greater than 30 mg/dL, respectively |
Dehne et al. [21], 1997 | Hypovolemia in surgical ICU patients | 49.1 | Normocaloric parenteral nutrition with versus without 12 mL/kg per day HES 200/0.5 | Acute renal failure |
Gentilini et al. [22], 1999 | Hospital treatment of ascites in cirrhotic patients unresponsive to bed rest and low-sodium diet | 62.1 | Diuretics with versus without 50 mL 25% albumin daily | Acute renal failure |
Sort et al. [23], 1999 | Spontaneous bacterial peritonitis | 61.0 | Intravenous cefotaxime with versus without 1.5 g/kg 20% albumin on day 1 plus 1.0 g/kg on day 3 | Greater than 50% SCr or BUN increase and, in patients without pre-existing renal failure, greater than 1.5 mg/dL SCr or greater than 30 mg/dL BUN |
Sola-Vera et al. [24], 2003 | Prevention of paracentesis-induced circulatory dysfunction in cirrhotic patients with ascites | 61.4 | 20% albumin versus saline starting 3 hours after paracentesis | Greater than 100% SCr increase to greater than 2 mg/dL |
Brunkhorst et al. [25], 2008 | Severe sepsis or septic shock | 64.7 | 10% pentastarch versus Ringer's lactate | Need for renal replacement therapya |
McIntyre et al. [26], 2008 | Early septic shock | 63.3 | 10% pentastarch versus normal saline | Requirement for dialysis during hospitalization |
Chen et al. [27], 2009 | Spontaneous bacterial peritonitis | 56.5 | Cephalosporins with versus without 50 mL 20% albumin on days 1 to 3 | Greater than 50% SCr increase and, in patients without pre-existing renal failure, greater than 1.5 mg/dL SCr |