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Table 1 Factors affecting respiratory mechanics

From: Clinical review: The ABC of weaning failure - a structured approach

Increased airway resistance

Reduced compliance

Tube (small diameter, sputum retention)

Chest wall

Central airways

   Edema

   Tracheostomy malposition

   Elevated abdominal pressure

   Sputum plug

   Pleural fluid and ascites

   Corpus alienum (after trauma)

   Obesity

   Tracheomalacia or tracheal stenosis

Lung

Small airways

   Intrinsic positive end-expiratory pressure

   Asthma and chronic obstructive pulmonary disease

   Alveolar filling (edema, pus, and collapse)

   Acute respiratory distress syndrome

   Pneumonia

 

   Interstitial lung disease and fibrosis