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Figure 4 | Critical Care

Figure 4

From: Inhibition of monocyte chemoattractant protein-1 prevents diaphragmatic inflammation and maintains contractile function during endotoxemia

Figure 4

Effects of MCP-1 inhibition on inflammatory gene expression in the septic diaphragm. (a) Representative RNase protection assays showing proinflammatory gene expression in diaphragms of mice pretreated with anti-MCP-1 antibody or isotypic control antibody (IgG) during sepsis. (b) Quantification of proinflammatory gene mRNA levels in the diaphragm, normalized to the L32 housekeeeping gene. *P < 0.05 for IgG control antibody versus anti-MCP-1 antibody pretreatment groups; +P < 0.05 for IgG control antibody versus saline groups.

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Critical Care

ISSN: 1364-8535