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Figure 1 | Critical Care

Figure 1

From: Inhibition of monocyte chemoattractant protein-1 prevents diaphragmatic inflammation and maintains contractile function during endotoxemia

Figure 1

Transcript levels of MCP-1 and its receptor in the septic diaphragm. (a) Representative RNase protection assay showing MCP-1 mRNA in the diaphragm. (b) Quantification of MCP-1 mRNA levels in the diaphragm, normalized to the L32 housekeeeping gene. *P < 0.05 for saline versus LPS groups; N/D, not detectable. (c) Quantification of mRNA levels of the MCP-1 receptor, CCR2 (open bars, tibialis anterior muscle; solid bars, diaphragm; S, saline control group; L, LPS group). *P < 0.05 for tibialis versus diaphragm under the same conditions; +P < 0.05 for saline versus LPS groups in the same muscle.

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