Skip to main content

Advertisement

Table 2 Underlying diagnoses and identification of clinically significant microorganisms in 221 ICU or surgical ward episodes (subset of data reported earlier [17])

From: Cost and mortality prediction using polymerase chain reaction pathogen detection in sepsis: evidence from three observational trials

  Totals PCR + episodes Share of PCR+ epsiodesbSh PCR+ BC+ episodes Share of BC+ epsiodesb Sh BC+
Total a 221 73 0.33 44 0.20
Underlying diagnoses a      
- Intra-abdominal sepsis 87 31 0.36 22 0.25
- Nosocomial pneumonia 80 28 0.35 21 0.26
- Community acquired pneumonia 6 1 0.17 0 0
- Multi-organ dysfunction syndrome 7 4 0.57 4 0.57
- Catheter related sepsis; post cardiac surgery 45 18 0.40 9 0.20
- Neutropenic fever 15 5 0.33 2 0.13
- Bone/joint infection 9 4 0.44 0 0
Other 46 11 0.24 3 0.07
  1. a underlying diagnoses do not add up to totals due to dual conditions
  2. b at least one clinically significant microorganism retrieved in one PCR, respectively in any of several (as in standard of care) BC tests.
  3. BC, blood culture (BC+: blood culture with clinically relevant microorganism identified, not counting contaminations that are immediately at reporting evident to the treating clinician); PCR, polymerase chain reaction (PCR+: PCR with clinically relevant microorganism identified. Note that in our study, all PCR+ reported microorganisms are considered clinically relevant.