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Figure 2 | Critical Care

Figure 2

From: Treatment of euvolemic hyponatremia in the intensive care unit by urea

Figure 2

Evolution of SNa in 35 patients with severe hyponatremia treated by urea and isotonic saline. (a) Daily evolution of SNa (mean ± SD) in 35 patients with severe hyponatremia (≤ 115 mEq/L) treated with isotonic saline and urea (*P < 0.001 compared to Day 0). (b) Daily evolution of SNa (mean ± SD) in 12 patients with severe hyponatremia (≤ 115 mEq/L) who received the first day only isotonic saline (1 or 2 L). The addition of urea increased significantly SNa (*P < 0.01 compared to Day 0). (c) Evolution of SNa (mean ± SD) each four hours in 10 patients with severe hyponatremia treated with 1 L isotonic saline over 12 hr and urea (0.5 g/kg) (P < 0.01 compared to time 0).

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